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Dr. Emina jasarevic, nd | Naturopathic physician

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Heart Health & Cholesterol – What women (and men) NEED to Know.
February 16, 2024
The Gender Gap Cardiovascular disease (CVD) or Coronary Artery Disease (CAD) is the…
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FAQ

What Causes Hypothyroidism?

Chronic Stress & Adrenal Fatigue

The adrenal glands take the leading role when it comes to managing stress through the production of cortisol. Research shows that adrenal fatigue has an impact on thyroid function. Even at a mild degree of deficiency, adrenal fatigue can negatively affect thyroid hormone conversion, utilization, and production. For example, high stress can cause too much cortisol in the circulation which promotes inflammation around the thyroid, and this reduces thyroid receptor responsiveness. Therefore, when treating thyroid issues with medicine or therapy it’s important to address the adrenals, this connection, and to care for them both effectively.

Hashimoto’s Hypothyroid

90% of cases of hypothyroidism are due to an autoimmune attack on the thyroid gland by either thyroperoxidase antibodies (TPOAb) or by thyroglobulin antibodies (TgAb), a condition called Hashimoto’s thyroiditis. What this means is that the body creates immune cells that attack the gland so that its function – and a person’s health – declines over time. This condition can be triggered by gluten in gluten-sensitive individuals. Similarly, in these people, gluten avoidance for at least 3 months may help lower antibody levels to a normal range.

Thyroid Conversion Disorder

In some cases, the conversion of T4 into T3 doesn’t function properly due an enzyme issue or otherwise. Test results will show normal levels of TSH and T4 but severely low levels of T3. Commonly, in these cases, patients are often told by their doctors that their thyroid function is “normal” even though they do not feel normal! This is also why some patients who receive medication or therapies that only supplement T4 levels may feel like the treatment is ineffective.

Thyroid Hormone Resistance

Thyroid hormone resistance can be thought of in the same way as insulin resistance is in diabetics. In this condition, the body’s cells are unresponsive to thyroid hormones. In these individuals, T3 and T4 levels can be normal but TSH levels are elevated.

Nutritional Deficiencies

For proper function and the creation of thyroid hormones, the thyroid gland requires the trace minerals iodine, selenium and zinc as well as an amino acid, thyroxine. Deficiency in any of these nutrients can create symptoms of hypothyroidism. Iodine is found in iodized salt and sea vegetables (such as nori and dulse flakes). I have come to find that iodine deficiency is more prevalent than previously given credit for (a 24 Hour Urine Iodine Challenge Test can determine this). The trace mineral Selenium is abundantly found in Oysters and Brazil nuts, and Zinc is rich in pumpkin seeds and beef. Thyroxine is the amino acid building block of thyroid hormones and can be found in most sources of protein.

Heavy Metal Toxicity and Mercury

The thyroid hormone and the heavy metal mercury have strikingly similar biochemistry. The long term exposure of this metal wreaks havoc on the thyroid gland and a person’s health, with these negative effects typically being experienced by dental patients who have currently have or previously had mercury amalgams. Sometimes it is prudent to screen for heavy metal toxicity and high levels of mercury that may be causing thyroid suppression. Heavy metal testing, followed by Chelation Therapy for removal of mercury from deep tissue stores is one naturopathic way to treat the underlying hypothyroid condition.

Central Hypothyroidism

In rare cases, disorders of the pituitary gland or hypothalamus in the brain may be an underlying cause for central Hypothyroidism (AKA secondary or tertiary hypothyroidism). There are usually other concerning symptoms (beyond the list seen on this page) that would warrant imaging and more advanced hospital testing.

If a patient comes to you seeking mental health assistance, what will their experience be like?

“They will be heard and acknowledged. We will look for potential nutrient deficiencies or toxicities and other barriers that can contribute to poor mental health.”

What are Adrenal Glands?

The adrenal glands are tiny hats, one each, that sit atop your kidneys and secrete hormones to help you deal with and manage stress. The outer part of the glands, called  the cortex, releases cortisol, for our stress response and metabolism control, as well as aldosterone to regulate blood pressure. The inner part of the glands are the medulla where adrenaline is released, another part of the stress response.

When your central nervous system perceives stress, it stimulates the adrenal glands to release their hormones as a part of the “fight or flight” response. This can happen several times throughout the day and can vary depending on your lifestyle. For example, an alarm clock startling you out of sleep will trigger this response, as will less sudden stressors like feeling overwhelmed by your overflowing email at work or worrying about finances or family members. In the early stages of stress, this response is actually beneficial. It can improve mental clarity, focus and energy. But over time, the benefits start to fade, and the consequences of chronic stress take over.

What is Adrenal Fatigue?

Adrenal Fatigue is a modern-day epidemic and results from the overstimulation of the adrenal glands due to chronic stress and over time, low cortisol levels. The most common report is feeling “burnt out”.

Adrenal fatigue is one of the most common health disorders, but it’s not recognized or screened for in conventional medicine – unless you have the extreme case of Addison’s or Cushing’s Disease – and these are uncommon. However, Adrenal Fatigue will impact up to 80% of us at some point our lives. Adrenal fatigue may occur after a major life-changing event such as divorce, surgery, childbirth, or even following a car accident.

The main purpose of your adrenals is to enable your body to deal with stress from every possible source, ranging from injury and disease to work and relationship problems. Adrenal function is of paramount importance because these small glands play a pivotal role in determining the way your body responds to every change in your internal and external environment. For example, the protective activity of anti-inflammatory adrenal hormones such as cortisol help to minimize reactions like swelling and inflammation in situations ranging from allergies to autoimmune disorders. These hormones closely involved in many metabolic processes:

  • Blood sugar regulation
  • Metabolism of carbohydrates and fats
  • Conversion of fats and proteins into energy
  • Distribution of stored fat  – focused around your waist (the spare tire); & sides of your face
  • Cardiovascular function
  • Gastrointestinal function

After mid-life (menopause in women, andropause in men), the adrenal glands gradually become the major source of the sex hormones circulating throughout the body in both men and women. These hormones themselves have a whole host of physical, emotional and psychological effects, from the level of your sex drive to the tendency to gain weight.

Adrenal fatigue causes a feeling of generalized “unwellness” which creates havoc on your life. In more serious cases, the activity of the adrenal glands is so diminished that you may have difficulty getting out of bed for more than a few hours per day. With each increment of reduction in adrenal function, every organ and system in your body is more profoundly affected. Metabolic changes occur in your carbohydrate, protein and fat metabolism, fluid and electrolyte balance, heart and cardiovascular system, and sex drive. Many other alterations take place at the biochemical and cellular levels in response to, and to compensate for, the decrease in adrenal hormones that occurs with adrenal fatigue.

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A fit body, a calm mind, a house full of love. These things cannot be bought – they must be earned.”
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